10. At Last: Erythropoietin as a Single Glycoform
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作者: Dr. Ping Wang, Dr. Suwei Dong, Dr. John A. Brailsford, Dr. Karthik Iyer, Dr. Steven D. Townsend, Dr. Qiang Zhang, Dr. Ronald C. Hendrickson, Dr. JaeHung Shieh, Dr. Malcolm A. S. Moore, Prof. Samuel J. Danishefsky*
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发布时间: 2012-11-07
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Angew. Chem. Int. Ed. 2012, 51, 11576-11584.
Dr. Ping Wang, Dr. Suwei Dong, Dr. John A. Brailsford, Dr. Karthik Iyer, Dr. Steven D. Townsend, Dr. Qiang Zhang, Dr. Ronald C. Hendrickson, Dr. JaeHung Shieh, Dr. Malcolm A. S. Moore, Prof. Samuel J. Danishefsky*
Wild thing : The first total synthesis of wild‐type erythropoietin glycoprotein (see picture) has been accomplished. The erythropoietic activity of the synthetic folded protein has been demonstrated.